When Perl isn't fast enough?
Perl fan for many years.
Recently developing a systems API. Did a benchmark. A simple response of pong to an http request. Mojolicious Vs go.
Perl was not fast. By a BIG order of magnitude.
The only thing you need to know when it comes to optimising code is very simple: You can never make code run faster. You can only make it do less.
I have had fun with Go, but I really hope they add something less verbose for error handling in a future version.