The Lancet affair set a really bad precedent and now I find myself distrusting every study on HCQ. The mortality differed by 2.2% which translates to ~30 extra deaths in the treatment vs. the control. Given the stakes here, Oxford should publish the data and protocols.

Can any Biostatisticians comment on the sample sizes and power analysis?

"‘A total of 1542 patients were randomised to hydroxychloroquine and compared with 3132 patients randomized to usual care alone. There was no significant difference in the primary endpoint of 28-day mortality (25.7% hydroxychloroquine vs. 23.5% usual care; hazard ratio 1.11 [95% confidence interval 0.98-1.26]; p=0.10). There was also no evidence of beneficial effects on hospital stay duration or other outcomes."

Source: https://www.recoverytrial.net/files/hcq-recovery-statement-0...