Not gonna lie: this vaccine made me sick as a dog for a couple of days. I would still get it again in a heartbeat. A couple of days under the weather vs a debilitating condition that can cause months of agony is a no-brainer. Longevity is a nice bonus, but it’s just that, a bonus.

Ask any family practice or gerontologist if shingles is a big deal. They’ll confirm that yes, you really, really want to avoid it.

Very interesting. I got this vaccine (needs to be taken twice) last year. Since then my back pain linked to possible beginning bechterews, which I have had for about a year, is gone and has stayed away for 2 months now. Could be unrelated, but it is so pronounced that I have been looking for an explanation. Very happy with it.

When I got the shingles vaccine two years ago it was the worst I've had in terms of site pain and general malaise, but certainly wasn't as bad as some people here are recounting.

My pharmacist said he knew someone who had gone blind in one eye from shingles, so that was a vivid motivator for me to get vaccinated!

Regards the mechanism, it seems ~35% of people get the shingles vaccination and you can imagine those are the people making most effort to live healthy and take precautions?

I had shingles aged ~60. I wonder if that gives any protection?

In Sweden the Shingrix vaccine is associated with reduced stroke and dementia.

https://sveavaccin.se/vaccinationer/baltros/

I wonder if the effects against inflammation could provide help against cancer. Cancers often cause themselves to be surrounded by inflammation to help feed them.

Frequent micro-dosing of anti-inflammatory medication (such as Aspirin) has been tried as cancer-prevention therapy before.

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Am I the only one who has a more circumspect reaction to such finding/claim? The idea that vaccines have unknown (since they're discovered much latter) effects very much separate from what they're supposed to do isn't reassuring to me...

AI says that is around 6-10 months extra life. Needed prodding to make the leap tho.