I can't find any mention of this in medical news sources; it sounds interesting, but the fact that it's being reported primarily by general interest media leaves me a bit skeptical.

Get raw honey. The processed kind loses these properties.

You can tell the quality, just turn over a jar you'll see a water bubble float up. The faster it rises the lower the quality. The raw type has none of that, just the good stuff.

Humans have been eating honey for the longest time. It's probably the best sweetener.

Honey is hygroscopic. It sucks the water out of bacteria and kills them. But anything hygroscopic does that, honey is not special in that way.

The article seems to conflate antibiotics (which kill bacteria living inside you) with topical treatments (which kill bacteria on you). You can't replace antibiotics with this.

As far as I know all honey does this, not just Manuka honey.